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The Board of Directors of the Company may at any time, and from time to time, amend, terminate, gold max viagra suspend one or more godl the Plans in any manner it deems appropriate, provided that such amendment, termination or suspension cannot adversely affect rights or obligations with respect to shares or options previously granted. The Board of Directors may not, without shareholder approval: make any amendment which gold max viagra materially modify the eligibility requirements for the Plans; increase or decrease the total number of shares of Common Stock which may be issued pursuant to the Plans except in the case of a reclassification of the Company's capital stock or a consolidation or merger of the Company; reduce the minimum option price per share; extend ma period for granting options; or materially increase in any other way the benefits accruing viagra generico en ecuador existieron employees who are eligible to participate in the Plans. The Plans are not qualified under Section 401(a) of the Internal Revenue Code, nor are they subject to any provisions of the Employee Retirement Income Security Act of 1974. Summary. The following sets forth certain information as of April 30, 2000, concerning the stock options and stock bonuses granted by the Company. Each option represents the right to purchase one share of the Company's common stock. Between September 1998 and April 30, 2000 the Company granted options to employees, consultants and third parties which collectively allow viaga the purchase of 1,310,466 shares of the Company's common stock. The options are exercisable at prices ranging between 0. 65 and 4.

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Mice (BalbC and C57B1) are injected intradermally or sub-cutaneously with 1 x 10 6 cells of the Bl 6 melanoma line. The tumour is allowed to grow until it is approximately 0. 5 gm in mass. The mice are then treated topically with in a microemulsion, for example, a microemulsion as described above in the microemulsion formulation examples 1 to 5 wherein the active agents include one or more of the following chemotherapeutic agents: 5 -fluorouracil (10 mgml, 20 microlitre dose, 2 times per day); Carboplatin (10 mgml, 20 microlitre dose, 2 times per day); Cis-Platinum (10 mgml, 20 microlitre dose, 2 times per day); or a control microemulsion without chemotherapeutic agents.

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